The quarter-final line-up for the Champions League will be completed this week, with Tuesday's ties both finely balanced.
Manchester United had David de Gea to thank for a battling 0-0 draw in Sevilla, but will be hoping to spend more time on the front foot at Old Trafford.
Roma have the benefit of an away goal from the first leg against Shakhtar Donetsk, but will need to score at least once to progress after losing 2-1.
Here we look at some of the best Opta numbers ahead of the two matches.
Roma v Shakhtar Donetsk
4 - Shakhtar Donetsk have won four of their five competitive games against Roma (L1), all in the Champions League.
52 - More than half of the teams who lose the first leg of a Champions League knockout game away from home 2-1 end up progressing (52 per cent - 12/23).
4 - However, Roma have been eliminated from all four Champions League knockout ties in which they have lost the first leg (home or away).
1 - The Ukrainian side are aiming to reach the Champions League quarter-finals for the first time since the 2010-11 campaign – which they did so by beating Roma 6-2 on aggregate in the round of 16.
3 -The Italian side have kept a clean sheet in each of their last three Champions League home games, winning the last two (D1).
Manchester United v Sevilla
1 - Manchester United have only lost one of their last nine home Champions League games against Spanish sides (W5 D3), that came against Real Madrid at this stage in 2012-13.
70 - Of the away sides who have drawn the first leg of a Champions League knockout tie 0-0, 70 per cent end up progressing to the next round (21/30).
15 - Manchester United haven't managed to score more than one goal in any of their last 15 Champions League encounters with Spanish opposition (seven goals in total).
0 - Sevilla have never won a Champions League game in England (D1 L3), with that one draw coming at Liverpool in this season's group stages.
1 - Starting with the 2011 final, Manchester United have only won one of their last eight Champions League knockout games (D3 L4).
7 - Jose Mourinho has only lost seven of his previous 69 Champions League home games as manager (W48 D14), though five of those defeats have been against Spanish opposition.
|Raiola rages over Italy´s Balotelli snub|
|Injured Saunders postpones Murray fight|
|PGA tightens security at Dell Match Play in wake of Austin bombings|
|Raiola hopes Reina to Milan hastens Donnarumma exit|
|F1 Raceweek: Hamilton prepares to begin title defence in Melbourne|
|Former Sevilla coach Berizzo eyeing return after beating cancer|
|Cutrone did not expect whirlwind Milan season and Italy call-up|
|Saints punish North for missing training|
|´Happy´ Kepa mulled over Real Madrid move|
|GGG wants Saunders next if Alvarez bout is called off|
|Former All Black Mika passes away|
|Lucas Vazquez keen on Real Madrid stay|
|South Africa delighted to call on ´world´s best´ Rabada|
|Tiger Woods continues climb in FedEx Cup, world rankings|
|Juventus clear Chiellini of serious injury|
|Newcastle charged as youth team allegedly breach advertising regulations|
|Kearney joins Best in extending Ireland contract|
|I did not betray Roma – Pjanic could not pass up Juventus opportunity|
|Cardiff Blues appoint Mulvihill as Wilson replacement|
|Title-chasing Sarri closes on Napoli renewal as he hopes to repay fans|
|Cook: I wasn´t close to quitting during Ashes|
|Messi and Ronaldo reveal World Cup kits|
|Nara praises Inter project as Icardi talks continue|
|Best to lead Ireland in World Cup after signing extension|
|Marseille´s Rami wants to ´tickle´ PSG|
|Fury targeting Louis´ record for title defences|
|Salah can push on to Messi´s level - Robertson|
|Rabada free to play in rest of South Africa-Australia series|
|F1 2018: Halo splits opinion ahead of Australia debut|
|Iniesta better than last year – Lopetegui|
|Federer yet to decide on clay-court season|
|Okon quits as Mariners head coach|
|LeBron triple-double powers Cavs past Bucks as Love returns|
|Lopetegui: Morata must earn World Cup spot|
|Ronaldo has asked about China – Scolari|
|Ebron signs two-year deal with Colts|
|Spieth, Reed to do battle in Match Play|
|Rangers´ Perez slaughtered, ate bull that caused broken elbow|
|Bills improve offensive line with Bodine, Newhouse|
|Braves phenom Acuna to start season in minors|
|Chargers add Pouncey on two-year deal|
|Ronaldo: I always show I´m the best|
|Joshua would love another Whyte tear-up, says Hearn|
|Manchester United not in Jorginho talks, says Napoli star´s agent|
|Hazard will not be false nine for Belgium, says Martinez|
|Bancroft confident on Starc and Marsh fitness|
|Mayweather to apply for MMA licence|
|Martial agent will not guarantee Manchester United stay|
|Del Potro and Djokovic on early collision course at Miami Open|
|Siemian swaps Broncos for Vikings|
|Broad chomping at the bit to bowl at Black Caps´ Taylor|
|Ronaldo slams ´fake news´ amid latest tax case claims|
|Van Dijk and Gundogan expect tough City-Liverpool tie|
|VAR to be introduced in Eredivisie|
|Di Biagio sees bright Italy future with Cutrone and Chiesa|
|Koeman won´t rule out Van Persie Netherlands return|
|I ate badly for years – how Messi solved his vomiting problem|
|England and Bath´s Watson out for the season|
|McLaren issues ´have been addressed´ ahead of F1 season opener|
|Tuchel feels he would still be at Dortmund without bomb attack|
|Pogba shows off new haircut as Ben Yedder trolls Man United star|
|Pogba cannot be happy but must focus on France, says Deschamps|
|Samuels slogs Windies closer to World Cup qualification|
|Having Rabada in third Test massive - Elgar|
|Cavs coach Lue steps away from job due to health reasons|
|Debuchy disappointed to be left out of latest France squad|
|Barton rejects England´s World Cup chances|
|Hamilton can become greatest F1 driver in history - Kovalainen|
|Sevilla coach Montella interested in Italy job|
|Football brain lacking, poor attitude and fourth choice – The Mourinho-Shaw saga at Manchester Unite|